A review of adjuvants for Leishmania vaccine candidates

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A review of adjuvants for Leishmania vaccine candidates

Over the last decade, there has been a flurry of research on adjuvants for vaccines, and several novel adjuvants are now licensed products or in late stage clinical development. The success of adjuvants in enhancing the immune response to antigens has led many researchers to re-focus their vaccine development programs. Although several vaccine candidates have been tested against leishmaniasis, ...

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nonencapsulated, nontypeable hemophilus influenzae (nthi) remains an important cause of acute otitis and respiratory diseases in children and adults. nthi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. the bacteria can also cause chronic dise...

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Modes of Action for Mucosal Vaccine Adjuvants

Vaccine adjuvants induce innate immune responses and the addition of adjuvants to the vaccine helps to induce protective immunity in the host. Vaccines utilizing live attenuated or killed whole pathogens usually contain endogenous adjuvants, such as bacterial cell wall products and their genomic nucleic acids, which act as pathogen-associated molecular patterns and are sufficient to induce adap...

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The advent of mass vaccination has saved millions of human lives and revolutionized the quality of life. Vaccination is currently one of the most cost effective ways of managing healthcare costs in both emerging and developed countries. Despite the long vaccine history and success, design and development of efficacious and safe vaccines has been traditionally semi-empirical. This is mainly due ...

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ژورنال

عنوان ژورنال: Journal of Biomedical Research

سال: 2010

ISSN: 1674-8301

DOI: 10.1016/s1674-8301(10)60004-8